Allegra ODT

Generic Name: fexofenadine (Oral route)

fex-oh-FEN-a-deen

Commonly used brand name(s)

In the U.S.

• Allegra


• Allegra ODT

Available Dosage Forms:

• Tablet


• Tablet, Disintegrating


• Capsule


• Suspension

Therapeutic Class: Respiratory Agent

Pharmacologic Class: Antihistamine, Less-Sedating

Chemical Class: Butyrophenone

Uses For Allegra ODT

Fexofenadine is an antihistamine. It is used to relieve the symptoms of hay fever (seasonal allergic rhinitis) and hives of the skin (chronic idiopathic urticaria) .

Antihistamines work by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. Also, in some people histamine can close up the bronchial tubes (air passages of the lungs) and make breathing difficult. Histamine can also cause some people to have hives, with severe itching of the skin .

This medicine is available only with your doctor's prescription .

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

Before Using Allegra ODT

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of fexofenadine in children below 6 months of age. Safety and efficacy have not been established .

Do not give any cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

Geriatric

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of fexofenadine in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment in the dose for patients receiving fexofenadine .

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Droperidol

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Aluminum Carbonate, Basic


• Aluminum Hydroxide


• Aluminum Phosphate


• Dihydroxyaluminum Aminoacetate


• Dihydroxyaluminum Sodium Carbonate


• Magaldrate


• Magnesium Carbonate


• Magnesium Hydroxide


• Magnesium Oxide


• Magnesium Trisilicate


• St John's Wort

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Apple Juice


• Grapefruit Juice


• Orange Juice

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body .

• Phenylketonuria—Use with caution. The oral disintegrating tablets contain phenylalanine .

Proper Use of fexofenadine

This section provides information on the proper use of a number of products that contain fexofenadine. It may not be specific to Allegra ODT. Please read with care.

You should always take this medicine with water. Do not take it with juice such as grapefruit, orange, or apple juice .

You should NOT take antacids that contain aluminum or magnesium hydroxide within 15 minutes of taking this medicine. If you are uncertain about this, ask your doctor or pharmacist .

For patients using the oral disintegrating tablet form of this medicine:

• Make sure your hands are dry.


• Do not push the tablet through the foil backing of the package. Instead, gently peel back the foil backing and remove the tablet.


• Immediately place the tablet on top of the tongue. Do not chew or break the tablet.


• The tablet will dissolve in seconds, and you may swallow it with your saliva. You may drink a glass of water after the tablet has dissolved.


• Always take this tablet on an empty stomach .

Shake the oral liquid well before using it. Measure the liquid with a marked measuring spoon, oral syringe, or medicine cup .

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For symptoms of hay fever:
  
  • For oral dosage form (capsules, tablets):
    
    • Adults and children 12 years of age and older—60 milligrams (mg) two times a day, or 180 mg once a day.
    
    
    • Children 6 to 11 years of age—30 mg two times a day.
    
    
    • Children 4 to 6 years of age—Use and dose must be determined by your doctor .
    
    
    • Children and infants up to 4 years of age—Use is not recommended .
    
    
  
  
  • For oral dosage form (disintegrating tablets):
    
    • Children 6 to 11 years of age—30 milligrams (mg) two times a day, on an empty stomach.
    
    
    • Children 4 to 6 years of age—Use and dose must be determined by your doctor .
    
    
    • Children and infants up to 4 years of age—Use is not recommended .
    
    
  
  
  • For oral dosage form (suspension):
    
    • Children 4 to 11 years of age—30 milligrams (mg) or 5 milliliters (mL) two times a day.
    
    
    • Children younger than 4 years of age—Use and dose must be determined by your doctor .
    
    
  
  

• For symptoms of chronic hives:
  
  • For oral dosage form (capsules, tablets):
    
    • Adults and children 12 years of age and older—60 milligrams (mg) two times a day, or 180 mg once a day.
    
    
    • Children 4 to 11 years of age—30 mg two times a day.
    
    
    • Children younger than 4 years of age—Use and dose must be determined by your doctor .
    
    
  
  
  • For oral dosage form (disintegrating tablets):
    
    • Children 4 to 11 years of age—30 milligrams (mg) two times a day, on an empty stomach.
    
    
    • Children younger than 4 years of age—Use and dose must be determined by your doctor .
    
    
  
  
  • For oral dosage form (suspension):
    
    • Children 4 to 11 years of age—30 milligrams (mg) or 5 milliliters (mL) two times a day.
    
    
    • Children 6 months to 4 years of age—15 mg or 2.5 mL two times a day.
    
    
    • Children younger than 6 months of age—Use and dose must be determined by your doctor .
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Allegra ODT

It is important that your doctor check your progress at regular visits to allow for changes in your dose and to help reduce any side effects .

Allegra ODT Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

• Chest tightness


• feeling of warmth, redness of the face, neck, arms and occasionally, upper chest


• large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs


• shortness of breath, difficult or labored breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Vomiting

Less common

• Back pain


• body aches or pain


• chills


• coughing


• diarrhea


• difficulty with moving


• dizziness


• ear congestion


• earache


• fever


• headache


• joint pain


• loss of voice


• muscle aching or cramping


• muscle pains or stiffness


• nasal congestion


• nausea


• pain in arms or legs


• pain or tenderness around eyes or cheekbones


• painful menstrual bleeding


• redness or swelling in ear


• ringing or buzzing in ears


• runny or stuffy nose


• sleepiness or unusual drowsiness


• sneezing


• sore throat


• stomach upset


• swollen joints


• unusual feeling of tiredness or weakness


• viral infection (such as cold and flu)

Rare

• Nervousness


• rash


• sleeplessness


• terrifying dreams


• trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Allegra ODT side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Allegra ODT resources

• Allegra ODT Side Effects (in more detail)
• Allegra ODT Use in Pregnancy & Breastfeeding
• Allegra ODT Drug Interactions
• Allegra ODT Support Group
• 1 Review for Allegra ODT - Add your own review/rating

• Allegra ODT Orally Disintegrating Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• Fexofenadine Prescribing Information (FDA)


• Allegra Prescribing Information (FDA)


• Allegra Monograph (AHFS DI)


• Allegra Consumer Overview


• Allegra MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Allegra ODT with other medications

• Hay Fever
• Urticaria

PediaCare Infant Drops

Generic Name: Pseudoephedrine (soo-doe-e-FED-rin)
Brand Name: Examples include Children's Dimetapp Decongestant Infant and PediaCare Infant

PediaCare Infant Drops are used for:

Relieving congestion due to colds, flu, and allergies. It may also be used for other conditions as determined by your doctor.

PediaCare Infant Drops are a decongestant. It works by reducing swelling and constricting blood vessels in the nasal passages, allowing you to breathe more easily.

Do NOT use PediaCare Infant Drops if:

• you are allergic to any ingredient in PediaCare Infant Drops


• you are taking furazolidone or have taken a monoamine oxidase (MAO) inhibitor (eg, phenelzine) in the last 14 days


• you have severe high blood pressure, severe heart blood vessel disease, a rapid heartbeat, or severe heart problems

Contact your doctor or health care provider right away if any of these apply to you.

Before using PediaCare Infant Drops:

Some medical conditions may interact with PediaCare Infant Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of heart problems, diabetes, glaucoma, an enlarged prostate or other prostate problems, adrenal gland problems, high blood pressure, seizures, stroke, blood vessel problems, or an overactive thyroid

Some MEDICINES MAY INTERACT with PediaCare Infant Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Rauwolfia derivatives (eg, reserpine) because the effectiveness of PediaCare Infant Drops may be decreased


• Beta-blockers (eg, propranolol), cocaine, furazolidone, indomethacin, methyldopa, MAO inhibitors (eg, phenelzine), oxytocic medicines (eg, oxytocin), rauwolfia derivatives (eg, reserpine), or tricyclic antidepressants (eg, amitriptyline) because the actions and side effects of PediaCare Infant Drops may be increased


• Bromocriptine, catechol-O-methyltransferase (COMT) inhibitors (eg, entacapone), digoxin, or droxidopa because the actions and side effects of these medicines may be increased


• Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because its effectiveness may be decreased by PediaCare Infant Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if PediaCare Infant Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use PediaCare Infant Drops:

Use PediaCare Infant Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take PediaCare Infant Drops with food, water, or milk to minimize stomach irritation.


• Use the dropper that comes with PediaCare Infant Drops to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.


• If you miss a dose of PediaCare Infant Drops and are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use PediaCare Infant Drops.

Important safety information:

• PediaCare Infant Drops may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to PediaCare Infant Drops. Using PediaCare Infant Drops alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.


• If your symptoms do not improve within 7 days or if you develop a high fever, check with your doctor.


• If you have trouble sleeping, ask your pharmacist or doctor about the best time to take PediaCare Infant Drops.


• Do not take diet or appetite control medicines while you are taking PediaCare Infant Drops.


• PediaCare Infant Drops contains pseudoephedrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains pseudoephedrine. If it does or if you are uncertain, contact your doctor or pharmacist.


• Diabetes patients - PediaCare Infant Drops may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.


• Use PediaCare Infant Drops with caution in the ELDERLY because they may be more sensitive to its effects.


• Use PediaCare Infant Drops with extreme caution in CHILDREN younger than 2 years of age. Safety and effectiveness in this age group have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using PediaCare Infant Drops during pregnancy. It is unknown if PediaCare Infant Drops are excreted in breast milk. If you are or will be breast-feeding while you are using PediaCare Infant Drops, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of PediaCare Infant Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Difficulty urinating; dizziness; headache; nausea; nervousness; restlessness; sleeplessness; stomach irritation.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: PediaCare Infant side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; hallucinations; irregular or unusually slow or rapid heartbeat; rapid breathing; seizures.

Proper storage of PediaCare Infant Drops:

Store PediaCare Infant Drops at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep PediaCare Infant Drops out of the reach of children and away from pets.

General information:

• If you have any questions about PediaCare Infant Drops, please talk with your doctor, pharmacist, or other health care provider.


• PediaCare Infant Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about PediaCare Infant Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More PediaCare Infant resources

• PediaCare Infant Side Effects (in more detail)
• PediaCare Infant Use in Pregnancy & Breastfeeding
• Drug Images
• PediaCare Infant Drug Interactions
• PediaCare Infant Support Group
• 8 Reviews for PediaCare Infant - Add your own review/rating

Compare PediaCare Infant with other medications

• Nasal Congestion

Paclitaxel Novaplus

Generic Name: paclitaxel (Intravenous route)

pak-li-TAX-el

Intravenous route(Solution)

Anaphylaxis and severe hypersensitivity reactions characterized by dyspnea and hypotension requiring treatment, angioedema, and generalized urticaria have occurred in clinical trials. Fatal reactions have occurred in patients despite premedication and all patients should be pretreated with corticosteroids, diphenhydramine, and H(2) antagonists. Patients who experience severe hypersensitivity reactions to paclitaxel should not be rechallenged with the drug. Paclitaxel therapy should not be given to patients with solid tumors who have baseline neutrophil counts of less than 1500 cells/mm(3) and should not be given to patients with AIDS-related Kaposi's sarcoma if the baseline neutrophil count is less than 1000 cells/mm(3). Monitor peripheral blood cell counts frequently .

Commonly used brand name(s)

In the U.S.

• Nov-Onxol


• Onxol


• Paclitaxel Novaplus


• Taxol

Available Dosage Forms:

• Solution

Therapeutic Class: Antineoplastic Agent

Pharmacologic Class: Mitotic Inhibitor

Uses For Paclitaxel Novaplus

Paclitaxel injection is used to treat advanced cancer of the ovaries, breast, non-small cell lung cancer, and Kaposi sarcoma. Kaposi sarcoma is a cancer of the skin and mucous membranes that is commonly found in patients with acquired immunodeficiency syndrome (AIDS).

Paclitaxel belongs to the group of medicines called antineoplastics. It interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected, other unwanted effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects may not be serious but may cause concern. Some effects may not occur until months or years after the medicine is used.

Before you begin treatment with paclitaxel, you and your doctor should talk about the good this medicine will do as well as the risks of using it.

This medicine is to be administered only by or under the immediate supervision of your doctor.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, paclitaxel is used in certain patients with the following medical conditions:

• Cancer of the bladder.


• Cancer of the cervix.


• Cancer of the endometrium.


• Cancer of the esophagus.


• Cancer of the fallopian tube or lining of the abdomen (spreading from the ovary).


• Cancers of the head and neck.


• Cancer of the prostate.


• Cancer of the stomach


• Cancer of the testes.


• Cancer of unknown primary site.


• Small cell lung cancer (a certain type found in the tissues of the lungs).

Before Using Paclitaxel Novaplus

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of paclitaxel injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of paclitaxel injection in the elderly. However, elderly patients are more likely to have unwanted side effects (e.g., heart disease, bone marrow problems, and nerve problems), which may require caution in patients receiving paclitaxel injection.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	D	Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Rotavirus Vaccine, Live

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Adenovirus Vaccine Type 4, Live


• Adenovirus Vaccine Type 7, Live


• Aprepitant


• Bacillus of Calmette and Guerin Vaccine, Live


• Bexarotene


• Cisplatin


• Deferasirox


• Doxorubicin Hydrochloride


• Ethinyl Estradiol


• Fosaprepitant


• Infliximab


• Influenza Virus Vaccine, Live


• Measles Virus Vaccine, Live


• Mumps Virus Vaccine, Live


• Pazopanib


• Rotavirus Vaccine, Live


• Rubella Virus Vaccine, Live


• Smallpox Vaccine


• St John's Wort


• Testosterone


• Tretinoin


• Typhoid Vaccine


• Valspodar


• Varicella Virus Vaccine


• Yellow Fever Vaccine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Dalfopristin


• Doxorubicin Hydrochloride Liposome


• Epirubicin


• Fosphenytoin


• Lapatinib


• Phenytoin


• Quinupristin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Bradycardia (slow heart rate) or


• Heart rhythm problems or


• Hypertension (high blood pressure) or


• Hypotension (low blood pressure) or


• Peripheral neuropathy (pain, numbness, or tingling of hands, arms, legs, or feet)—Use with caution. May make these conditions worse.

• Infection—May decrease your body's ability to fight an infection.

• Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

• Neutropenia, severe (very low white blood cells)—Should not be used in patients with this condition.

Proper Use of paclitaxel

This section provides information on the proper use of a number of products that contain paclitaxel. It may not be specific to Paclitaxel Novaplus. Please read with care.

Medicines used to treat cancer are very strong and can have many unwanted effects. Before receiving this medicine, you and your doctor should talk about the good this medicine will do as well as the risks of using it. .

A doctor or other trained health professional will give you this medicine in a hospital or cancer treatment center. This medicine is given through a needle placed in one of your veins.

This medicine is usually given every 3 weeks and is used together with other cancer medicines, such as cisplatin or doxorubicin.

You may also receive other medicines to help prevent allergic reactions and nausea or vomiting from paclitaxel.

Precautions While Using Paclitaxel Novaplus

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.

This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor or nurse right away if you have a cough; dizziness; wheezing; trouble with breathing; chest or throat tightness; swelling in your face or hands; fever; chills; rash; itching or hives; skin redness; or lightheadedness or faintness while you are receiving this medicine.

While you are being treated with paclitaxel, and after you stop treatment with it, do not have any immunizations (vaccines) without your doctor's approval. Paclitaxel may lower your body's resistance and the vaccine may not work as well or you might get the infection the vaccine is meant to prevent. In addition, you should not be around other persons living in your household who receive live virus vaccines because there is a chance they could pass the virus on to you. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. Do not get close to them and do not stay in the same room with them for very long. If you have questions about this, talk to your doctor.

Paclitaxel can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:

• If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.


• Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in the urine or stools; or pinpoint red spots on your skin.


• Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done.


• Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime.


• Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters.


• Avoid contact sports or other situations where bruising or injury could occur.

This medicine may cause peripheral neuropathy. Check with your doctor right away if you are having burning, numbness, tingling, or painful sensations in the arms, hands, legs, or feet while using this medicine.

Cancer medicines can cause diarrhea, nausea, or vomiting in most people, sometimes even after receiving medicines to prevent it. Ask your doctor or nurse about other ways to control these unwanted effects if you still have nausea or vomiting after receiving the medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Paclitaxel Novaplus Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

• Black or tarry stools


• blurred vision


• burning, numbness, tingling, or painful sensations


• confusion


• cough or hoarseness with fever or chills


• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position


• feeling of warmth


• fever or chills


• lower back or side pain


• painful or difficult urination


• pale skin


• redness of the face, neck, arms, and occasionally, upper chest


• shortness of breath


• skin rash or itching


• sore throat


• sweating


• troubled breathing with exertion


• ulcers, sores, or white spots in the mouth


• unsteadiness or awkwardness


• unusual bleeding or bruising


• unusual tiredness or weakness


• weakness in the arms, hands, legs, or feet

Less common

• Blood in the urine or stools


• difficult or labored breathing


• pinpoint red spots on the skin


• shortness of breath (severe)


• slow heartbeat


• tightness in the chest


• wheezing

Incidence not known

• Anxiety


• blue lips, fingernails, or skin


• difficult or troubled breathing


• fainting


• fast heartbeat


• irregular, fast or slow, or shallow breathing


• sudden shortness of breath

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site


• cracked lips


• diarrhea


• difficulty with swallowing


• hair loss


• nausea or vomiting


• numbness, burning, or tingling in the hands or feet


• pain in the joints or muscles, especially in the arms or legs


• thinning of the hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Paclitaxel Novaplus resources

• Paclitaxel Novaplus Use in Pregnancy & Breastfeeding
• Paclitaxel Novaplus Drug Interactions
• Paclitaxel Novaplus Support Group
• 2 Reviews for Paclitaxel Novaplus - Add your own review/rating

• Onxol Prescribing Information (FDA)


• Onxol MedFacts Consumer Leaflet (Wolters Kluwer)


• Paclitaxel Professional Patient Advice (Wolters Kluwer)


• Paclitaxel Prescribing Information (FDA)


• Paclitaxel Monograph (AHFS DI)


• Paclitaxel MedFacts Consumer Leaflet (Wolters Kluwer)


• Taxol Prescribing Information (FDA)


• Taxol Consumer Overview

Compare Paclitaxel Novaplus with other medications

• Breast Cancer
• Breast Cancer, Adjuvant
• Breast Cancer, Metastatic
• Kaposi's Sarcoma
• Non-Small Cell Lung Cancer
• Ovarian Cancer
• Wilms' Tumor

Amnesteem

Generic Name: isotretinoin (oral) (EYE so TRET i noyn)

Brand Names: Amnesteem, Claravis, Sotret

What is isotretinoin?

Isotretinoin is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly.

Isotretinoin is used to treat severe nodular acne that has not responded to other treatments, including antibiotics.

Isotretinoin may also be used for purposes not listed in this medication guide.

What is the most important information I should know about isotretinoin?

Isotretinoin can cause severe, life-threatening birth defects. Never use isotretinoin if you are pregnant.

Women of child-bearing potential must agree in writing to use two specific forms of birth control and have regular pregnancy tests before, during, and after taking isotretinoin.

Isotretinoin is available only under a special program called iPLEDGE. It is dangerous to try and purchase isotretinoin on the Internet or from vendors outside of the United States.

Do not take vitamin supplements containing vitamin A while you are taking isotretinoin. Do not donate blood while taking isotretinoin and for at least 30 days after you stop taking it.

What should I discuss with my healthcare provider before taking isotretinoin?

Isotretinoin is available only under a special program called iPLEDGE. You must be registered in the program and sign documents stating that you understand the dangers of this medication and that you agree to use birth control as required by the program. Ask your doctor or call the drug maker if you have questions about the program or the written requirements.

It is dangerous to try and purchase isotretinoin on the Internet or from vendors outside of the United States. The sale and distribution of isotretinoin outside of the iPLEDGE program violates the regulations of the U.S. Food and Drug Administration for the safe use of this medication.

Do not use this medication if you are allergic to isotretinoin or to parabens, or if you are pregnant or may become pregnant.

To make sure you can safely take isotretinoin, tell your doctor if you have any of these other conditions:

• 
  

  a personal or family history of depression or mental illness;

  
  


• 
  

  heart disease, high cholesterol or triglycerides;

  
  


• 
  

  osteoporosis or other bone disorders;

  
  


• 
  

  an intestinal disorder such as inflammatory bowel disease, ulcerative colitis, or Crohn's disease;

  
  


• 
  

  diabetes;

  
  


• 
  

  asthma;

  
  


• 
  

  an eating disorder (anorexia nervosa); or

  
  


• liver disease.

Isotretinoin can cause severe, life-threatening birth defects if the mother takes the medication during pregnancy. Even one dose of isotretinoin can cause major birth defects of the baby's ears, eyes, face, skull, heart, and brain. Never use isotretinoin if you are pregnant.

For Women: Unless you have had your uterus and ovaries removed (total hysterectomy with oophorectomy) or have been in menopause for at least 12 months in a row, you are considered to be of child-bearing potential.

Even women who have had their tubes tied are required to use birth control while taking isotretinoin.

You must have a negative pregnancy test 30 days before you start taking isotretinoin. A pregnancy test is also required before each prescription is refilled, right after you take your last dose of isotretinoin, and again 30 days later. All pregnancy testing is required by the iPLEDGE program.

You must agree in writing to use two specific forms of birth control beginning 30 days before you start taking isotretinoin and ending 30 days after you stop taking it. Both a primary and a secondary form of birth control must be used together.

Primary forms of birth control include:

• 
  

  tubal ligation (tubes tied);

  
  


• 
  

  vasectomy of the male sexual partner;

  
  


• 
  

  an IUD (intrauterine device);

  
  


• 
  

  estrogen-containing birth control pills (not mini-pills); and

  
  


• 
  

  hormonal birth control patches, implants, injections, or vaginal ring.

  
  

Secondary forms of birth control include:

• 
  

  a male latex condom plus spermicidal foam or gel;

  
  


• 
  

  a diaphragm plus spermicidal foam or gel;

  
  


• 
  

  a cervical cap plus spermicidal foam or gel; and

  
  


• 
  

  a vaginal sponge containing spermicide.

  
  

Stop using isotretinoin and call your doctor at once if you have unprotected sex, if you quit using birth control, if your period is late, or if you think you might be pregnant. If you get pregnant while taking isotretinoin, call the iPLEDGE pregnancy registry at 1-866-495-0654.

It is not known whether isotretinoin passes into breast milk. Do not take isotretinoin without first talking to your doctor if you are breast-feeding a baby.

How should I take isotretinoin?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Each prescription of isotretinoin must be filled within 7 days of the date it was prescribed by your doctor. You will receive no more than a 30-day supply of isotretinoin at one time.

Always take isotretinoin with a full glass of water to prevent the capsule from melting in your esophagus (food pipe), causing irritation. Do not chew or suck on the capsule. Swallow it as quickly as possible. Take isotretinoin with food or milk. Take this medication for the entire length of time prescribed by your doctor. Your acne may seem to get worse at first, but should then begin to improve.

To be sure this medication is not causing harmful effects, your blood may need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.

Never share this medicine with another person, even if they have the same symptoms you have. Store at room temperature away from moisture, heat, and light.

See also: Amnesteem dosage (in more detail)

What happens if I miss a dose?

Skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include headache, dizziness, vomiting, stomach pain, warmth or tingling under the skin, swelling of the lips, and loss of balance or coordination.

What should I avoid while taking isotretinoin?

Do not take vitamin supplements containing vitamin A while you are taking isotretinoin. Do not donate blood while taking isotretinoin and for at least 30 days after you stop taking it. Donated blood that is later given to pregnant woman could lead to birth defects in her baby if the blood contains any level of isotretinoin.

Do not use wax hair removers or have dermabrasion or laser skin treatments while you are taking isotretinoin and for at least 6 months after you stop taking it. Scarring may result.

Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Isotretinoin can make your skin more sensitive to sunlight and sunburn may result. Isotretinoin may impair your vision, especially at night. Be careful if you drive or do anything that requires you to see clearly.

Isotretinoin side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using isotretinoin and call your doctor at once if you have any of these serious side effects:

• 
  

  depressed mood, trouble concentrating, sleep problems, crying spells, aggression or agitation, changes in behavior, hallucinations, thoughts of suicide or hurting yourself;

  
  


• 
  

  sudden numbness or weakness, especially on one side of the body;

  
  


• 
  

  blurred vision, sudden and severe headache or pain behind your eyes, sometimes with vomiting;

  
  


• 
  

  hearing problems, hearing loss, or ringing in your ears;

  
  


• 
  

  seizure (convulsions);

  
  


• 
  

  severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;

  
  


• 
  

  loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

  
  


• 
  

  severe diarrhea, rectal bleeding, black, bloody, or tarry stools;

  
  


• 
  

  fever, chills, body aches, flu symptoms, purple spots under your skin, easy bruising or bleeding;

  
  


• 
  

  severe blistering, peeling, and red skin rash; or

  
  


• 
  

  joint stiffness, bone pain or fracture.

  
  

Less serious side effects may include:

• 
  

  joint pain, back pain;

  
  


• 
  

  feeling dizzy, drowsy, or nervous;

  
  


• 
  

  dryness of the lips, mouth, nose, or skin; or

  
  


• 
  

  cracking or peeling skin, itching, rash, changes in your fingernails or toenails.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect isotretinoin?

Tell your doctor about all other medicines you use, especially:

• 
  

  steroids (prednisone and others);

  
  


• 
  

  seizure medication such as phenytoin (Dilantin); or

  
  


• 
  

  a tetracycline antibiotic such as demeclocycline (Declomycin), doxycycline (Doryx, Vibramycin), minocycline (Minocin), or tetracycline (Brodspec, Sumycin, Tetracap).

  
  

This list is not complete and other drugs may interact with isotretinoin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Amnesteem resources

• Amnesteem Side Effects (in more detail)
• Amnesteem Dosage
• Amnesteem Use in Pregnancy & Breastfeeding
• Drug Images
• Amnesteem Drug Interactions
• Amnesteem Support Group
• 13 Reviews for Amnesteem - Add your own review/rating

• Amnesteem Prescribing Information (FDA)


• Amnesteem Advanced Consumer (Micromedex) - Includes Dosage Information


• Accutane MedFacts Consumer Leaflet (Wolters Kluwer)


• Accutane Prescribing Information (FDA)


• Accutane Consumer Overview


• Claravis Prescribing Information (FDA)


• Isotretinoin Monograph (AHFS DI)


• Sotret Prescribing Information (FDA)

Compare Amnesteem with other medications

• Acne
• Acute Nonlymphocytic Leukemia
• Granuloma Annulare
• Melanoma, Metastatic
• Rosacea

Where can I get more information?

• Your pharmacist can provide more information about isotretinoin.

See also: Amnesteem side effects (in more detail)

Amoxicillin Suspension

Pronunciation: a-MOX-i-SIL-in
Generic Name: Amoxicillin
Brand Name: Generic only. No brands available.

Amoxicillin Suspension is used for:

Treating infections caused by certain bacteria. It is also used with other medicines to treat Helicobacter pylori infection and ulcers of the small intestines.

Amoxicillin Suspension is a penicillin antibiotic. It works by killing sensitive bacteria.

Do NOT use Amoxicillin Suspension if:

• you are allergic to any ingredient in Amoxicillin Suspension or another penicillin antibiotic (eg, ampicillin)


• you have recently received or will be receiving live oral typhoid vaccine


• you have infectious mononucleosis (mono)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Amoxicillin Suspension:

Some medical conditions may interact with Amoxicillin Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of allergies, asthma, hay fever, or hives


• if you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness) to a cephalosporin (eg, cephalexin) or another beta-lactam antibiotic (eg, imipenem)


• if you have kidney problems or gonorrhea

Some MEDICINES MAY INTERACT with Amoxicillin Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Anticoagulants (eg, warfarin) because the risk of bleeding may be increased


• Probenecid because it may increase the amount of Amoxicillin Suspension in your blood


• Chloramphenicol, macrolide antibiotics (eg, erythromycin), sulfonamides (eg, sulfamethoxazole), or tetracycline antibiotics (eg, doxycycline) because they may decrease Amoxicillin Suspension's effectiveness


• Methotrexate because the risk of its side effects may be increased by Amoxicillin Suspension


• Live oral typhoid vaccine or hormonal birth control (eg, birth control pills) because their effectiveness may be decreased by Amoxicillin Suspension

This may not be a complete list of all interactions that may occur. Ask your health care provider if Amoxicillin Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Amoxicillin Suspension:

Use Amoxicillin Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Amoxicillin Suspension by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• Shake well before each use.


• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.


• Amoxicillin Suspension may be mixed with formula, milk, fruit juice, water, ginger ale, or other cold drinks. If you mix Amoxicillin Suspension, take it at once after mixing. Be sure that the entire dose is swallowed.


• To clear up your infection completely, take Amoxicillin Suspension for the full course of treatment. Keep taking it even if you feel better in a few days.


• If you miss a dose of Amoxicillin Suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Amoxicillin Suspension.

Important safety information:

• Amoxicillin Suspension may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Amoxicillin Suspension with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Amoxicillin Suspension only works against bacteria; it does not treat viral infections (eg, the common cold).


• Be sure to use Amoxicillin Suspension for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.


• Long-term or repeated use of Amoxicillin Suspension may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.


• Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.


• Hormonal birth control (eg, birth control pills) may not work as well while you are using Amoxicillin Suspension. To prevent pregnancy, use an extra form of birth control (eg, condoms).


• Brown, yellow, or gray tooth discoloration has occurred rarely in some patients taking Amoxicillin Suspension. It occurred most often in children. The discoloration was reduced or removed by brushing or dental cleaning in most cases. Contact your doctor if you experience this effect.


• Diabetes patients - Amoxicillin Suspension may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.


• Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed if you use Amoxicillin Suspension for a long period of time. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Amoxicillin Suspension with caution in the ELDERLY; they may be more sensitive to its effects, especially patients with kidney problems.


• Use Amoxicillin Suspension with extreme caution in CHILDREN younger than 10 years old who have diarrhea or an infection of the stomach or bowel.


• Caution is advised when using Amoxicillin Suspension in CHILDREN younger than 3 months old; they may be more sensitive to its effects.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Amoxicillin Suspension while you are pregnant. Amoxicillin Suspension is found in breast milk. If you are or will be breast-feeding while you use Amoxicillin Suspension, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Amoxicillin Suspension:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; confusion; dark urine; fever, chills, or persistent sore throat; red, swollen, blistered, or peeling skin; seizures; severe diarrhea; stomach pain or cramps; unusual bruising or bleeding; vaginal discharge or irritation; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Amoxicillin side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include decreased urination.

Proper storage of Amoxicillin Suspension:

Store Amoxicillin Suspension in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. If necessary, it may be stored at room temperature. Store away from heat, moisture, and light. Do not store in the bathroom. Throw away any unused medicine after 14 days. Keep Amoxicillin Suspension out of reach of children and away from pets.

General information:

• If you have any questions about Amoxicillin Suspension, please talk with your doctor, pharmacist, or other health care provider.


• Amoxicillin Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Amoxicillin Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Amoxicillin resources

• Amoxicillin Side Effects (in more detail)
• Amoxicillin Use in Pregnancy & Breastfeeding
• Drug Images
• Amoxicillin Drug Interactions
• Amoxicillin Support Group
• 49 Reviews for Amoxicillin - Add your own review/rating

Compare Amoxicillin with other medications

• Actinomycosis
• Anthrax Prophylaxis
• Bacterial Endocarditis Prevention
• Bacterial Infection
• Bladder Infection
• Bronchitis
• Chlamydia Infection
• Cutaneous Bacillus anthracis
• Dental Abscess
• Helicobacter Pylori Infection
• Lyme Disease, Arthritis
• Lyme Disease, Carditis
• Lyme Disease, Erythema Chronicum Migrans
• Lyme Disease, Neurologic
• Otitis Media
• Pneumonia
• Sinusitis
• Skin Infection
• Tonsillitis/Pharyngitis
• Upper Respiratory Tract Infection
• Urinary Tract Infection

Arimidex

Pronunciation: an-AS-troe-zole
Generic Name: Anastrozole
Brand Name: Arimidex

Arimidex is used for:

Treating breast cancer in certain women who have been through menopause, including women with disease progression after tamoxifen therapy. It may also be used for other conditions as determined by your doctor.

Arimidex is an aromatase inhibitor. It works by lowering blood estradiol concentrations, which may decrease the size and growth of the tumor.

Do NOT use Arimidex if:

• you are allergic to any ingredient in Arimidex


• you have not gone through menopause


• you are pregnant, think you may be pregnant, or plan to become pregnant


• the patient is a man or a child


• you are taking estrogen-containing products (eg, certain birth control pills or hormone replacement therapies) or tamoxifen

Contact your doctor or health care provider right away if any of these apply to you.

Before using Arimidex:

Some medical conditions may interact with Arimidex. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of liver problems, osteoporosis (weak bones), heart or blood vessel problems (eg, ischemic heart disease), or high cholesterol or lipid levels

Some MEDICINES MAY INTERACT with Arimidex. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Estrogen-containing products (eg, certain birth control pills or hormone replacement therapies) or tamoxifen because they may decrease Arimidex's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Arimidex may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Arimidex:

Use Arimidex as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient information leaflet is available with Arimidex. Talk to your pharmacist if you have questions about this information.


• Take Arimidex by mouth with or without food.


• If you miss a dose of Arimidex, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If more than 1 dose is missed, contact your doctor or pharmacist.

Ask your health care provider any questions you may have about how to use Arimidex.

Important safety information:

• Arimidex may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Arimidex with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Arimidex lowers the amount of estrogen in your body, which may cause your bones to become softer and weaker. This may increase your chance of bone fractures, especially of the spine, hip, and wrist. Discuss any questions or concerns with your doctor.


• Lab tests, including blood cholesterol, bone mineral density, or liver function, may be performed while you use Arimidex. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Arimidex should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Do not use Arimidex if you are pregnant. It has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor right away. It is not known if Arimidex is found in breast milk. Do not breast-feed while taking Arimidex.

Possible side effects of Arimidex:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Anxiety; back, bone, breast, joint, muscle, or pelvic pain; constipation; cough; diarrhea; dizziness; flu-like symptoms (eg, muscle aches, tiredness); hair loss; headache; hot flashes; loss of appetite; mild stomach pain; nausea; sore throat; stomach upset; sweating; trouble sleeping; vaginal dryness; vomiting; weakness; weight gain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness); burning, numbness, or tingling sensation; calf or leg pain, swelling, or tenderness; chest pain; confusion; fainting; fever, chills, or persistent sore throat; frequent or painful urination; mental or mood changes (eg, depression); numbness of an arm or leg; one-sided weakness; red, swollen, blistered, or peeling skin; severe or persistent bone pain; severe or persistent dizziness or headache; severe or persistent tiredness or weakness; shortness of breath; skin lesions, ulcers, or blisters; speech problems; swelling of the arms or legs; swollen lymph nodes; symptoms of liver problems (eg, yellowing of the skin or eyes; dark urine; severe or persistent nausea, vomiting, or stomach pain; general feeling of being unwell); tingling, pain, coldness, or weakness in the fingers, wrists, or hands; vaginal bleeding or unusual discharge; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Arimidex side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Arimidex:

Store Arimidex at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Arimidex out of the reach of children and away from pets.

General information:

• If you have any questions about Arimidex, please talk with your doctor, pharmacist, or other health care provider.


• Arimidex is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Arimidex. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Arimidex resources

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Aquacillin

Dosage Form: FOR ANIMAL USE ONLY
Drug Facts

Description General Information

Procaine penicillin G is a potent antibacterial agent which is effective against a variety of pathogenic organisms, chiefly in the Gram-positive category. Aquacillin is a free-flowing product prepared by combining penicillin G and procaine, molecule for molecule, with dispersing agents.

Residue Warnings

RESIDUE WARNINGS: (FDA Requested Revision) 100mL & 250mL-Label

Milk taken from animals during treatment and for 48 hours (4 milkings) after the latest treatment must not be used for food. A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal.

Discontinue use of this drug for the following time periods before treated animals are slaughtered for food: Cattle-10 days, Sheep-9 days, Swine-7 days. Not for use in horses intended for food.

RESIDUE WARNINGS:(FDA Requested Revision) 100mL & 250mL-Onsert

Milk that has been taken from animals during treatment and for 48 hours (4 milkings) after the latest treatment must not be used for food. A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal.

Discontinue use of this drug for the following time periods before treated animals are slaughtered for food: Cattle-10 days, Sheep-9 days, Swine-7 days. Not for use in horses intended for food.

WARNING: (Old revision) 500mL-Label

Milk taken from animals during treatment and for 48 hours (4 milkings) after the latest treatment must not be used for food. A withdrawal period has not been established for this product in preruminating calves. Do not use in veal calves.

Discontinue use of this drug for the following time periods before treated animals are slaughtered for food: Cattle-10 days, Sheep-9 days, Swine-7 days. Not for use in horses intended for food.

WARNING: (Old revision) 500mL-Onsert

Milk that has been taken from animals during treatment and for 48 hours (4 milkings) after the latest treatment must not be used for food. A withdrawal period has not been established for this product in preruminating calves. Do not use in veal calves.

Discontinue use of this drug for the following time periods before treated animals are slaughtered for food: Cattle-10 days, Sheep-9 days, Swine-7 days. Not for use in horses intended for food.

Aquacillin is a registered trademark of VEDCO, Inc.

LOT

EXP DATE

760001

Directions for Use

Aquacillin should be administered by the intramuscular route. A thoroughly cleaned, sterile needle and syringe should be used for each injection (needles and syringes may be sterilized by boiling in water for 15 minutes). Before withdrawing the solution from the bottle, disinfect the rubber cap on the bottle with a suitable disinfectant such as 70 percent alcohol. The injection site should be similarly cleaned with the disinfectant. Needles of 16 to 18 gauge and 1 to 1½ inches long are adequate for intramuscular injection.

INTRAMUSCULAR INJECTION: In livestock, intramuscular injection should be made by directing the needle of suitable gauge and length into the fleshy part of a thick muscle such as the rump, hip, or thigh region; avoid blood vessels and major nerves. Before injecting the solution, pull back gently on the plunger. If blood appears in the syringe, a blood vessel has been entered; withdraw the needle and select a different site. No more than 10mL should be injected at any one site in adult livestock; rotate injection sites for each succeeding treatment.

Care of sick animals: The use of antibiotics in the management of disease is based on an accurate diagnosis and an adequate course of treatment. When properly used in the treatment of diseases caused by penicillin-susceptible organisms. Most animals treated with Aquacillin show a noticeable improvement within 24 to 48 hours. If improvement does not occur within this period of time, the diagnosis and course of treatment should be re-evaluated. It is recommended that the diagnosis and treatment of animal diseases be carried out by a veterinarian. Since many diseases look alike but require different types of treatment, the use of professional veterinary and laboratory services can reduce treatment time, cost, and needless losses. Good housing, sanitation, and nutrition are important in the maintenance of healthy animals and are essential in the treatment of disease

Contains

Each mL of Aquacillin contains 300,000 units of procaine penicillin G and approximately: 0.08% sodium citrate; 0.15% sodium carboxymethylcellulose; 25% sorbitol solution; 0.06% povidone; 0.6% lecithin; 0.1% methylparaben; 0.01% propylparaben; 0.25% phenol.

Store between 2°-8°C (36°-46°F)

Restricted Drug (California)

Refer to package insert for complete directions.

 SHAKE WELL BEFORE USING.

Manufactured for VEDCO, Inc.

Manufactured By Teva Animal Health, Inc. Fort Dodge, IA 50501

Front Panel Label

Aquacillin

Penicillin-G Procaine In Aqueous Suspension

Injectable Antibiotic

For the treatment of disease in cattle, swine, sheep and horses.

For Intramuscular Use Only.

NOT FOR HUMAN USE

USE ONLY AS DIRECTED

NADA 65-110, Approved by FDA

Indications

INDICATIONS: (FDA Requested Revision) 100mL & 250mL-label

Aquacillin is recommended for treatment of bacterial pneumonia (shipping fever) caused by Pasteurella multocida in cattle and sheep, erysipelas caused by Erysipelothrix rhusiopathiae in swine, and strangles caused by streptococcus equi in horses.

INDICATIONS: (Old reversion) 500mL-label

Aquacillin is recommended for treatment of bacterial pneumonia (shipping fever) caused by Pasteurella multocida in cattle and sheep, erysipelas caused by Erysipelothrix insidiosa in swine, and strangles caused by streptococcus equi in horses.

DOSAGE LEVELS: The recommended daily dosage of penicillin is 3,000 units per pound of body weight (one mL per 100lb body weight). Continue daily treatment until recovery is apparent and for at least 1 day after symptoms disappear, usually in 2 or 3 days. Treatment should not exceed 4 consecutive days.

Precautions

Exceeding the highest recommended daily dosage of 3,000 units per pound of body weight, administering at recommended levels for more than 4 consecutive days, and/or exceeding 10mL intramuscularly per injection site may result in antibiotic residues beyond the withdrawal time.

Aquacillin should be injected deep within the fleshy muscles of the hip, rump, round, or thigh. Do not inject this material subcutaneously (under the skin), into a blood vessel, or near a major nerve.

Procaine penicillin G is a substance of low toxicity. However, side effects, or so-called allergic or anaphylactic reactions-sometimes fatal, have been known to occur in animals hypersensitive to penicillin and procaine. Such reactions can occur unpredictably with varying intensity. Animals administered Aquacillin should be kept under close observation for at least one-half hour. Should allergic or anaphylactic reactions occur, discontinue use of the product and immediately administer epinephrine following manufacturer’s recommendations; call a veterinarian. As with all antibiotic preparations, use of this drug may result in overgrowth of non-susceptible organisms, including fungi. A lack of response by the treated animal, or the development of new signs or symptoms suggest that an overgrowth of non-susceptible organisms has occurred. In such instances, consult your veterinarian. Since bactericidal drugs may interfere with the bacteriostatic action of tetracyclines, it is advisable to avoid giving penicillin in conjunction with tetracyclines. Penicillin-G should be stored between 2-8°C (36-46°F). Warm to room temperature and shake before using.

Directions

A thoroughly cleaned, sterile needle and syringe should be used for each injection (needles and syringes may be sterilized by boiling in later for 15 minutes). Before withdrawing the solution from the bottle, disinfect the rubber cap on the bottle with a suitable disinfectant such as 70 percent alcohol. The injection site should be similarly cleaned with the disinfectant. Needles of 16 to 18 gauge and not more than 1 to 1½ inch long are adequate for injections.

A subcutaneous injection should be made by pinching up a fold of the skin between the thumb and forefinger. The mid-neck region is the preferred injection site. Insert the needle under the fold in a direction approximately parallel to the surface of the body. When the needle is inserted in this manner the medication will be delivered underneath the skin between the skin and the muscles. Proper restraint, such as the use of a chute and nose lead, is needed for proper administration of the product.

SHAKE WELL BEFORE USING

FOR ANIMAL USE ONLY

RESTRICTED DRUG (CALIFORNIA)

USE ONLY AS DIRECTED

NOT FOR HUMAN USE

Storage

Store between 2°-8°C (36°-46°F)

Restricted Drug (California)-Use Only As Directed

Refer to label insert for complete directions.

SHAKE WELL BEFORE USING.

760001-

Rev

Manufactured By Teva Animal Health, Inc. Fort Dodge, IA 50501

Package Information

Aquacillin available in vials of 100mL, 250mL and 500mL with each mL containing 300,000 units of procaine penicillin G. The 500mL vial is intended for use with automatic syringes

FOR ANIMAL USE ONLY

RESTRICTED DRUG (California)

USE ONLY AS DIRECTED.

NOT FOR HUMAN USE.

Principle Display Panel

Principle Display Panel

Principle Display Panel

Aquacillin  penicillin g procaine  injection, suspension

Product Information Product Type OTC ANIMAL DRUG NDC Product Code (Source) 50989-660 Route of Administration INTRAMUSCULAR DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength PENICILLIN G PROCAINE (PENICILLIN G) PENICILLIN G PROCAINE 300000 ug  in 1 mL

Inactive Ingredients Ingredient Name Strength No Inactive Ingredients Found

Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 50989-660-12 100 mL In 1 BOTTLE, GLASS None 2 50989-660-15 250 mL In 1 BOTTLE, GLASS None 3 50989-660-16 500 mL In 1 BOTTLE, GLASS None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
NADA	NADA65110	07/18/2003	07/31/2009

Labeler - Vedco, Inc. (021634266)

Revised: 02/2010Vedco, Inc.